The colors of the nodes represent different domains. The width of the edges is proportional to the absolute value of the edge-weight. (A: Baseline B: Month 12) Blue edges indicate positive associations and red edges indicate negative associations. Including individual item scores of PHQ-9 as measures of depression. Secondary networks depicting partial correlations between fatigue and variables of physical disability, affective disorders, cognitive performance, sleep quality, and structural brain imaging. Abbreviation: FSS=Fatigue Severity Scale EDSS=Expanded Disability Status Scale zT25FW= Z score of Timed 25 Foot Walk test BMI=Body Mass Index z9-HPT= Z score of Nine Hole Peg Test zPASAT=Z score of Paced Auditory Serial Addition Test SDMT=Symbol Digit Modality Test PHQ-9=Patient Heath Questionnaire-9 GAD-7=Generalized Anxiety Disorder-7 instrument SLEEP = Multiple Sclerosis Impact Scale-problems sleeping WMH=Whole-brain white matter hyperintensity volume cGM=cortical grey matter volume BG=basal ganglia volume THALA=thalamus volume.įig. The colours of the nodes represent different domains. Including PHQ-9 sum scores as measures of depression. Primary networks depicting partial correlations between fatigue and variables of physical disability, affective disorders, cognitive performance, sleep quality, and structural brain imaging.
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